Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
67-64-1	Acetone		200-662-2

Hazard Symbols: XI F
Risk Phrases: 11 36 66 67

Section 3 - Hazards Identification

Not available.
Target Organs: Kidneys, central nervous system, liver, respiratory system, skin.


Potential Health Effects
Eye: Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury.
Skin: Exposure may cause irritation characterized by redness, dryness, and inflammation.
Ingestion: May cause irritation of the digestive tract. May cause central nervous system depression, kidney damage, and liver damage. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma.
Inhalation: Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause liver and kidney damage. May cause motor incoordination and speech abnormalities. May cause narcotic effects in high concentration.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation may cause effects similar to those of acute inhalation.

Section 4 - First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. Wash mouth out with water.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Vapor may cause flash fire.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam.
Flash Point: -20 deg C ( -4.00 deg F)
Autoignition Temperature: 465 deg C ( 869.00 deg F)
Explosion Limits, Lower:2.80 vol %
Upper: 13.20 vol %
NFPA Rating: 1 - health, 3 - flammability, 0 - instability

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wear appropriate protective clothing to minimize contact with skin. Remove all sources of ignition.

Section 7 - Handling and Storage

Handling: Use with adequate ventilation. Use spark-proof tools and explosion proof equipment. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container. Flammables-area.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
Acetone	500 ppm TWA; 750 ppm STEL	250 ppm TWA; 590 mg/m3 TWA 2500 ppm IDLH	1000 ppm TWA; 2400 mg/m3 TWA

OSHA Vacated PELs: Acetone: 750 ppm TWA; 1800 mg/m3 TWA
Personal Protective Equipment
Eyes: Not available.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear polyethylene gloves, apron, and/or clothing.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - Physical and Chemical Properties

Physical State: Clear liquid
Appearance: colorless - APHA: 10 max
Odor: sweetish odor
pH: Not available.
Vapor Pressure: 231 mm Hg @ 25 deg C
Vapor Density: 2.0
Evaporation Rate:7.7 (n-Butyl acetate=1)
Viscosity: Not available.
Boiling Point: 56.2 deg C @ 760.00mm Hg
Freezing/Melting Point:-94 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:.7857g/cm3
Molecular Formula:CH3COCH3
Molecular Weight:58.08

Section 10 - Stability and Reactivity

Chemical Stability: Stable.
Conditions to Avoid: Incompatible materials, moisture, exposure to air, temperatures above 220°C.
Incompatibilities with Other Materials: Oxidizing agents, reducing agents, bases, acetic acid, nitric acid, sulfuric acid, May form explosive/incompatible mixtures with a wide range of substances., hydrogen peroxides, chromyl chloride, nitrosyl perchlorate, hexachloromelamine, chromic anhydride, sulfur dichloride, carbon, potassium-tert-butoxide, peroxomonosulfuric acid.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information

RTECS#:
CAS# 67-64-1: AL3150000
LD50/LC50:
CAS# 67-64-1:
Dermal, guinea pig: LD50 = >9400 uL/kg;
Draize test, rabbit, eye: 10 uL Mild;
Draize test, rabbit, eye: 20 mg Severe;
Draize test, rabbit, eye: 20 mg/24H Moderate;
Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, mouse: LC50 = 44 gm/m3/4H;
Inhalation, rat: LC50 = 50100 mg/m3/8H;
Oral, mouse: LD50 = 3 gm/kg;
Oral, rabbit: LD50 = 5340 mg/kg;
Oral, rat: LD50 = 5800 mg/kg;
Carcinogenicity:
CAS# 67-64-1:
ACGIH: A4 - Not Classifiable as a Human Carcinogen
Epidemiology: No information available.
Teratogenicity: No developmental toxic effects were seen in rats and mice exposed to atmospheric concentrations of acetone vapour up to 11,000 ppm and 6000 ppm respectively 6 hr/day for 7 day. [Mast, T.J; et al. Energy Res. Abstr. 1989, 14(7), Abstr. No. 13672]
Reproductive Effects: Fertility: post-implantation mortality. Ihl, mam: TCLo=31500 ug/m3/24H (1-13D preg)
Neurotoxicity: No information available.
Mutagenicity: Cytogenetic analysis: hamster fibroblast, 40 g/L Sex chromosome loss/non-disjunction: S.cerevisiae, 47600 ppm Salmonella typhimurium TA92, TA94, TA98, TA100, TA1535, TA1537 with metabolic activation negative. Chinese hamster fibroblast (24 hr) without metabolic activation induced chromosomal aberrations. [Ishidate, M; et al. Food Chem. Toxicol. 1984, 22(8), 623-636]
Other Studies: See actual entry in RTECS for complete information.

Section 12 - Ecological Information

Ecotoxicity: No data available. Rainbow trout LC50:5540 mg/L/96H Sunfish (tap water), death at 14250 ppm/24H Mosquito fish (turbid water) TLm=13000 ppm/48H Harlequin fish LC50:5700 ppm/24H Daphnia magna ED50:10 mg/l/24,48H Brine shrimp LD50:2100 mg/l/24,48H at 24øC
Environmental: Volatilizes, leeches, and biodegrades when released to soil.
Physical: No information available.
Other: On soil, substance volatilizes and biodegrades.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 67-64-1: waste number U002 (Ignitable waste).

Section 14 - Transport Information

	US DOT	IATA	RID/ADR	IMO	Canada TDG
Shipping Name:	No information available.				No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information

US FEDERAL

TSCA
CAS# 67-64-1 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
CAS# 67-64-1: 4/12b
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA

CERCLA Hazardous Substances and corresponding RQs
CAS# 67-64-1: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 67-64-1: acute, chronic, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 67-64-1 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XI F
Risk Phrases:
R 11 Highly flammable.
R 36 Irritating to eyes.
R 66 Repeated exposure may cause skin dryness or
cracking.
R 67 Vapors may cause drowsiness and dizziness.

Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 9 Keep container in a well-ventilated place.

WGK (Water Danger/Protection)
CAS# 67-64-1: 0
Canada - DSL/NDSL
CAS# 67-64-1 is listed on Canada's DSL List.
Canada - WHMIS
WHMIS: Not available.
Canadian Ingredient Disclosure List
CAS# 67-64-1 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 67-64-1: OEL-AUSTRALIA:TWA 500 ppm (1185 mg/m3);STEL 1000 ppm
OEL-AUSTRIA:TWA 750 ppm (1780 mg/m3) OEL-BELGIUM:TWA 750 ppm (1780 mg
/m3);STEL 1000 pp OEL-CZECHOSLOVAKIA:TWA 800 mg/m3;STEL 4000 mg/m3 O
EL-DENMARK:TWA 250 ppm (600 mg/m3) OEL-FINLAND:TWA 500 ppm (1200 mg/m
3);STEL 625 ppm (1500 mg/m3) OEL-FRANCE:TWA 750 ppm (1800 mg/m3) OEL
-GERMANY:TWA 1000 ppm (2400 mg/m3) OEL-HUNGARY:TWA 600 mg/m3;STEL 120
0 mg/m3 OEL-INDIA:TWA 750 ppm (1780 mg/m3);STEL 1000 ppm (2375 mg/m3)
OEL-JAPAN:TWA 200 ppm (470 mg/m3) OEL-THE NETHERLANDS:TWA 750 ppm (
1780 mg/m3) JAN9 OEL-THE PHILIPPINES:TWA 1000 ppm (2400 mg/m3) OEL-P
OLAND:TWA 200 mg/m3 OEL-RUSSIA:TWA 200 ppm;STEL 200 mg/m3 OEL-SWEDEN
:TWA 250 ppm (600 mg/m3);STEL 500 ppm (1200 mg/m3) OEL-SWITZERLAND:TW
A 750 ppm (1780 mg/m3) OEL-TURKEY:TWA 1000 ppm (2400 mg/m3) OEL-UNIT
ED KINGDOM:TWA 750 ppm (1810 mg/m3);STEL 1250 ppm OEL IN BULGARIA, CO
LOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE,
VIETNAM check ACGI TLV

Section 16 - Additional Information

MSDS Creation Date: 3/20/2003
Revision #0 Date: Original.

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.